Definitions:

1. in a disagreeable manner adverb
   • it's so plaguey cold!

Synonyms:

• annoying
• bothersome
• disagreeably
• galling
• irritating
• nettlesome
• pesky
• pestering
• pestiferous
• pestilent
• pestilential
• plaguy
• teasing
• vexatious
• vexing