Definitions:

1. To bring about feelings of sorrow, grief, or disappointment. VERB
   • The news of her mother's passing deeply saddened her.
2. To cause to become sad. VERB
   • The sight of the neglected children saddened the volunteers.
3. To make someone feel sad or to cause sorrow or unhappiness. VERB
   • It saddened me to see to see so much hatred in the world.
   • The news of their death saddened me deeply.

Synonyms:

• break one's heart
• depress
• dismay
• distress
• upset