Definitions:

1. A local infection induced in humans by inoculation with the virus causing cowpox, in order to confer resistance to smallpox; normally lasts three weeks and leaves a pitted scar. NOUN
   • Vaccinia is known for its characteristic pustular lesions at the vaccination site.
2. A virus used in the smallpox vaccine and is crucial in the eradication of smallpox. NOUN
   • The introduction of the vaccinia virus vaccine marked a turning point in the fight against smallpox, leading to its eventual eradicaction.
3. An infection of cowpox, or the virus which causes the infection. NOUN
   • Scientists are exploring the use of the vaccinia virus in cancer therapy due to its ability to target and kill tumor cells.
4. Is a virus that is part of the Orthopoxvirus genus, which also includes variola, the virus that causes smallpox, and cowpox. NOUN
   • The smallpox vaccine, which contains the vaccinia virus, was essential in eradicating the disease worldwide.

Synonyms:

• cowpox
• smallpox vaccine
• variola
• variola vaccine
• variola vaccinia