Definitions:

1. In a zoological sense, might be used to describe the physical attributes of animals that resemble those of traditional pachyderms. ADJECTIVE
   • The pachydermic skin of the elephant serves as a protective barrier against environmental hazards and predators.
2. In medicine, could describe human skin that is abnormally thick, similar to the skin of a pachyderm. ADJECTIVE
   • Research into pachydermic species has provided valuable insight into evolutionary adaptations for survival in harsh conditions.
3. Mataphorically, describing a person, might imply that they are unresponsive or insensitive to emotional expressions or nuances, akin to being "thick-skinned". ADJECTIVE
   • Her pachydermic response to the harsh criticisms showed a remarkable level of composure and detachment.
4. Refers to something related or characteristic of pachyderms. ADJECTIVE
   • The pachydermic legs of the elephant provided it with immense strength and stability.

Synonyms:

• callous
• indurate
• pachydermal
• pachydermatous