Definitions:

1. Biological process or condition wherein vacuoles, or small cavities or spaces within a cell, are formed or present. NOUN
   • the study focused on the mechanism behind vacuolation in response to nutrient starvation.
2. Formation into, or multiplication, of vacuoles. NOUN
   • Vacuolation can be an indicator of cellular damage or stress in both plant and animal cells.
3. The process of forming vacuoles within the cytoplasm of a cell. NOUN
   • Researchers observed increased vacuolation in the liver cells of the treated mice.
4. The state of having become filled with vacuoles. NOUN
   • The doctor was surprised by how much vacuolation the tissue had.
   • The vacuolation of the plant cell was a clear sign of their adaptation to the drought conditions.

Synonyms:

• cavitation
• vacuolar alteration
• vacuole formation
• vacuolisation
• vacuolization