Definitions:

1. A biological process or condition in which vacuoles or empty spaces form within or between cells. NOUN
   • The vacuolization of the cells was evident under the microscope, suggesting a reaction to nutrient deprivation.
2. Refers to the process of forming vacuoles within the cytoplasm of a cell. NOUN
   • In certain types of cell injury, vacuolization can be a marker of cellular distress.
3. The formation of vacuoles or vacuole-like structures, within or adjacent to cells. NOUN
   • The biologist observed increase vacuolization in the plant cells exposed to salt stress.
4. The state of having become filled with vacuoles. NOUN
   • Vacuolization in the neurons was one of the key pathological features noted in the brain tissue of the affected patients.

Synonyms:

• vacuolation
• vacuolisation